News media often do not report potential sources of bias in medical research

News articles often fail to report pharmaceutical company funding and frequently refer to medications by their brand names, both potential sources of bias, according to a new study of news media coverage of medical studies

New articles represent an important source of medical information for many patients, and even some physicians, says the study, which has been published in the October 1 issue of JAMA. "An increasingly recognised source of commercial bias in medical research is the funding of studies by companies with a financial interest in the results," the authors wrote. Little is known about how frequently news articles report the funding sources of the medical research they report on, or how frequently news articles use brand medication names instead of generic names, which could create commercial bias.

Michael Hochman, MD, of the Cambridge Health Alliance and Harvard Medical School, Cambridge, Massachusetts, and colleagues reviewed US news articles from newspaper and online sources about pharmaceutical-funded medication studies to determine how frequently and prominently they indicate the funding source and how often they refer to medications by their brand vs generic names.

The studies were published in five major general medical journals (JAMA, New England Journal of Medicine, Lancet, Archives of Internal Medicine and the Annals of Internal Medicine). The researchers also surveyed editors at the 100 most widely circulated newspapers in the US about their publications' practices on the reporting of company funding and the use of generic medication names.

The authors identified 306 news articles, of which 175 were from newspapers and 131 were from online sources. Among the 306 news articles about company-funded medication studies, the funding source for the studies was not reported in 42 per cent of the articles. There was no significant difference in nonreporting rates between articles obtained from newspaper and online sources. Of the 306 news articles, 277 concerned medications with both generic and brand names. Among these 277 articles, 38 per cent used only brand names and 67 per cent used brand names in at least half of the medication references.

The survey of newspaper editors found that 88 per cent indicated that his/her publication often or always reported company funding in articles about medical research, and that 77 per cent reported that they often or always referred to medications by the generic names in articles about medical research. Three per cent of editors indicated that their publication had a written policy stating that company funding should be reported in articles about medical research, while the editor at two per cent of newspapers responded that his/her publication had a written policy stating that medications should be referred to predominantly by their generic names.

However, the editors' perceptions diverged from their publications' actual performances. A total of 104 newspaper articles were analysed from publications for which editors reported always identifying company funding. Of these articles, 45 per cent failed to cite company funding. Additionally, a total of 75 newspaper articles were analysed from publications for which the editors reported always using generic names. Of these articles, 76 per cent used brand names in at least half of the medication references.

"Our findings raise several concerns. For patients and physicians to evaluate new research findings, it is important that they know how the research was funded so they can assess whether commercial biases may have affected the results. Additionally, the use of generic medication names by the news media is preferable so that physicians and patients learn to refer to medications by their generic names, a practice that is likely to reduce medication errors and may decrease unnecessary health care costs," the authors wrote.

Date Posted: 2 October 2008 Last Modified: 2 October 2008